Currently, there are two known primary cannabinoid receptors: CB1 and CB2 receptors.
CB1 receptors are primarily located in the central nervous system, and in some peripheral tissues. These receptors affect appetite, muscle control, pain, cognition, thermoregulation, and our stress response.
CB2 receptors are primarily found in immune cells and at a lower density in the central nervous system. CB2 activation is associated with immune cell proliferation and inflammation.